Page 313 - Glucose Monitoring Devices
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320    CHAPTER 15 Automated closed-loop insulin delivery




                         (A)
                                             /    Mean CGM   /    ± Std.dev. CGM    Set-point
                            250
                                                  Target zone   Hypo-/hyperglycemia
                           (mg/dL)  200


                           CGM  150

                            100
                             50
                                                   1                   2                   3
                                                          Time(h)
                         (B)
                            1.4
                                                            /    Mean Basal  /  ± Std.dev. Basal
                            1.2
                           Insulin(U/h)  0.8
                              1


                           Basal  0.6
                            0.4
                            0.2
                              0
                                                   1                   2                   3
                                                          Time(h)
                         (C)
                            3.5
                                                            /    MeanBolus  /  ± Std.dev. Bolus
                              3
                            2.5
                           Bolus Insulin (U)  1.5
                              2


                              1
                            0.5
                              0
                                                   1                   2                   3
                                                          Time(h)
                         FIGURE 15.7
                         Closed-loop results for the exercise period (first one-hour) and the postexercise recovery
                         periods (2 h succeeding exercise) for the sAP (blue) and mAP (red) systems.
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