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214                                                                    Flow Sensors

          9.1   Introduction to Microfluidics and Applications for Micro Flow
          Sensors

                 Micromachining has numerous applications in fluidics, and its use in this area has
                 become even more important as people strive to create complete fluidic systems in
                 miniaturized formats. A broad range of devices and systems can be found in the
                 books Microfluidic Technology and Applications [4] and Micromachined Trans-
                 ducers Sourcebook [5], as well as in various review articles published [6–10]. A brief
                 introduction to microfluidics relevant for flow sensors and applications for micro
                 flow sensors is given in this chapter. The first and most obvious microfluidic devices
                 to integrate with a flow sensor were micropumps and/or valves, to form dosing sys-
                 tems or mass flow controllers [11–17]. Schematics of two typical dosing systems are
                 depicted in Figure 9.1.
                    Further integration took place including several pumps, valves, flow sensors,
                 and micromixers to form microanalysis systems (µTAS) [18–20]. As an example, a
                 microfluidic system using two pumps, two flow sensors, and a mixer is shown in Fig-
                 ure 9.2 [21]. A microsystem for measurement of flow rate, pressure, temperature,
                 conductivity, UV-absorption, and fluorescence on a single quartz glass chip was pre-
                 sented by Norlin et al. [22]. Another multisensor chip designed for catheter applica-
                 tions has been presented by Goosen et al. [23] and Tanase et al. [24]. It includes
                 blood flow, pressure, and oxygen saturation level sensing.
                    The automotive industry has been, and is still one of the major driving forces for
                 MEMS-based sensors. For example, in engine control applications, the number of
                 sensors used will increase from approximately 10 in 1995, to more than 30 in 2010
                 [25]. The micromachined flow sensor has already made the jump into the automo-
                 bile industry [25–27]. Electronic fuel injection systems need to know the mass flow
                 rate of air sucked into the cylinders to meter the correct amount of fuel. Other areas
                 of application are in pneumatics, bioanalysis [20], metrology (wind velocity and
                 direction [28, 29]), civil engineering (wind forces on building), the transport and
                 process industry (fluidic transport of media, combustion, vehicle performance),
                 environmental sciences (dispersion of pollution), medical technology (respiration
                 and blood flow, surgical tools [30]), indoor climate control (ventilation and air con-
                 ditioning [31]), and home appliances (vacuum cleaners, air dryers, fan heaters).
                 Flow sensors have even been used in space applications. The microinstrument for
                 life science research, developed at the University of Neuchatel, Switzerland, included

















                 Figure 9.1  Schematics: (a) Monolithically assembled dosing system. (After: [12].) (b) Hybrid
                 dosing system. (After: [11].)
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