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1.3 Miniaturized Systems with Microoptics and Micromechanics  19

                                                Bow-tie antenna



                                                      Electrostatic
                              500                     actuator
                              mm                                    1.6                  10mm
                                                                   Gap spacing (mm)  0.8  Measured gap
                                                    Springs         1.4
                                                                    1.2
                                                    Glass substrate  1
                                                                    0.6
                                                                    0.4
                                                                    0.2
                                                                     0
                                                                                80
                                                                      0    40 Calculated gap 120  160
                                                                           Applied voltage (V)
                            Fig. 1.23. A bow–tie probe with an actuator driven by electrostatic force is fabri-
                            cated to provide a narrow gap that enhances the intensity of the near field. Reprinted
                            from [1.46] with permission by M. Esashi, Tohoku University, Japan




                                                                        waste
                                                Optical mixer

                                               Sample

                                                 Reagent          Microchannel
                            Fig. 1.24. Conceptual drawing of the future micrototal analysis system (µ-TAS)
                            [1.50]


                            and intersectingchannels [1.49] to induce chaotic behavior of a flow have
                            been fabricated. An optically driven micromixer [1.50] has been proposed to
                            stir a liquid directly, which is described in detail in Chap. 4. Highly sensitive
                            detection methods [1.51] and high-performance micropumps [1.52] are also
                            important because of the reaction between small liquids, as well as to drive
                            liquids in microchannels.
                               Optical inspection of a human body is also a useful method for minimally
                            invasive diagnosis and treatment. Figure 1.25 shows the microconfocal opti-
                            cal scanningmicroscope (m-COSM) [1.53]. The probe, 2.4 mm in diameter,
                            consists of a 2-D electrostatic scanner which is placed in front of the end of
                            the optical fiber. Light reflected by the tissue is collected by the same objec-
                            tive lens and reflected back into the same optical fiber. The field of view is
                            100 µm × 100 µm and the resolution is 1 µm with an image feed speed of 4
                            frames s −1 .
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