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L1592_frame_C22  Page 194  Tuesday, December 18, 2001  2:43 PM









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                                                         Initial Design

                                                 Augment            Change
                                                the Design          Settings
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                                          Check     Replicate    Relocate  Rescale
                                          quadratic
                                          effects
                       FIGURE 22.7  Some of the modifications that are possible with a two-level factorial experimental design. It can be stretched
                       (rescaled), replicated, relocated, or augmented.
                       of interactions as well as the effects of changing the three factors. Figure 22.6b is a two-level, three-
                       factor design in eight runs that can describe a smooth nonplanar surface. The Box-Behnken design (c)
                       and the composite two-level, three-factor design (d) can describe quadratic effects (maxima and minima).
                       The Box-Behnken design uses 12 observations located on the face of the cube plus a center point. The
                       composite design has eight runs located at the corner of the cube, plus six “star” points, plus a center
                       point. There are advantages to setting the corner and star points equidistant from the center (i.e., on a
                       sphere having a diameter equal to the distance from the center to a corner).
                        Designs (b), (c), and (d) can be replicated, stretched, moved to new experimental regions, and expanded
                       to include more factors. They are ideal for iterative experimentation (Chapters 43 and 44).


                       Iterative Design

                       Whatever our experimental budget may be, we never want to commit everything at the beginning. Some
                       preliminary experiments will lead to new ideas, better settings of the factor levels, and to adding or
                       dropping factors from the experiment. The oil emulsion-breaking example showed this. The importance
                       of iterative experimentation is discussed again in Chapters 43 and 44. Figure 22.7 suggests some of the
                       iterative modifications that might be used with two-level factorial experiments.


                       Comments

                       A good experimental design is simple to execute, requires no complicated calculations to analyze the
                       data, and will allow several variables to be investigated simultaneously in few experimental runs.
                        Factorial designs are efficient because they are balanced and the settings of the independent variables
                       are completely uncorrelated with each other (orthogonal designs). Orthogonal designs allow each effect
                       to be estimated independently of other effects.
                        We like factorial experimental designs, especially for treatment process research, but they do not solve
                       all problems. They are not helpful in most field investigations because the factors cannot be set as we
                       wish. A professional statistician will know other designs that are better. Whatever the final design, it
                       should include replication, randomization, and blocking.
                        Chapter 23 deals with selecting the sample size in some selected experimental situations. Chapters
                       24 to 26 explain the analysis of data from factorial experiments. Chapters 27 to 30 are about two-level
                       factorial and fractional factorial experiments. They deal mainly with identifying the important subset of
                       experimental factors. Chapters 33 to 48 deal with fitting linear and nonlinear models.

                       © 2002 By CRC Press LLC
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