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                     mass integration (Cont.):     Mechanical Engineering Faculty,
                       water integration and, 105–106  Paderborn University, 300
                       water minimization via      MER. See Maximal Energy Recovery
                           mathematical optimization,   MILP. See mixed integer linear
                           118–122                     program
                       water pinch analysis introduction,   MINLP. See mixed integer nonlinear
                           113–116                     program
                     material recovery pinch diagram   MIPSYN, 207–208
                         (MRPD):                   mistakes. See pitfalls
                       flow-rate targeting and, 116–117  mixed integer linear program (MILP),
                       fruit juice production, limiting   25, 29, 160. See also successive
                           water data and, 117         mixed integer linear program
                       MRPD for pure/impure fresh    convexity case-by-case
                           resource, 117                 evaluation, 28
                     materials reuse-recycle:        described, 27
                       construction of interval flow rate   deterministic methods for
                           diagram, 136                  solving, 31–32
                       material balance in aggregate   global optimality and, 29
                           planning, 137             mass balances/problems, 36
                       property pinch analysis and,   nodes/evaluation tree of, 31–32
                           133–136                 mixed integer nonlinear program
                       supply chain CCs and, 138       (MINLP), 25, 27
                     mathematical modeling suites:   deterministic methods for solving,
                       MATLAB, 210–211                   31–32
                       MATLAB alternatives, 211      mass balances/problems, 36
                       software tools, 210–211     model building and optimization,
                     mathematical optimization         24–25
                       fruit juice production, MRPD and   components, 24–25
                           network design, 119       examples, 24
                       illustrative example of brewery   IT-domain diagrams/UML
                           plant, 120–122                diagrams, 24
                       introduction to, 118–119    model creation, 33–43
                       water minimization via, 118–122  conceptual modeling, 34–35
                     Mathematical Programming (MPR)   equation construction, 35–37
                         approach, 8, 14             evaluating adequacy and precision,
                       model building/optimization       42–43
                           and, 24                   graph-theoretical approach, 35
                       model nonlinearity and, 41–42  handling model nonlinearity, 41
                       Network Pinch and, 17         handling process complexity, 38–40
                       network-related information   mass balances, 36–37
                           transformation, 35        objective function choice, 37–38
                       PI and, 14                    object-oriented modeling, 38–39
                       process optimization frameworks   P-graph framework, 35
                           and, 151–153              process insight application, 40–41
                       process synthesis major steps   Modelica modeling language, 24,
                           and, 153                    211–212
                       superstructure formulation,   molten-carbonate fuel
                           35–36, 38                   cells (MCFCs), 4
                       tools for designing chemical   MPR. See Mathematical Programming
                           processes, 20               (MPR) approach
                     MATLAB, 24, 29, 210–211       MRPD. See material recovery pinch
                     Maximal Energy Recovery (MER), 39  diagram
                     Maximal Structure Generation (MSG)   MSG algorithm. See Maximal
                         algorithm, 38, 157–158, 192   Structure Generation algorithm
                     MCFCs. See molten-carbonate fuel   multiple utilities targeting:
                         cells                       construction of GCCs and, 63
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