Page 123 - Thermodynamics of Biochemical Reactions

6.7 Calculation of the Equilibrium Composition for Glycolysis 119

Table 6.4 Equilibrium Compositions (M) for the First
Five Reactions of Glycolysis at 298.15 K, pH 7, Ionic Strength
0.25 M, and Specified Concentrations of ATP and ADP
[ATP] = lo-' M [ADP] = M
[ATP] = lo-* M [ADP] = lo-' M

[Glc]/M 1.20 x 10-6 1.24 x lo-'"
IG6PI/M 2.31 x 2.39 x lo-'
[F6PI/M 6.39 x 10- 6.61 x 10-7
lFBPl/M 7.64 x 7.90 x 10-
[GAPlM 1.79 x lo-" 1.82 x 10-4
[GlycPlM 3.94 x 10-3 4.00 x
Source: With permission from R. A. Alberty, Biophys. Chem. 93, 1 - 10
(200 1).

an example of that and emphasizes the fact that there is no loss of information in
making a Legendre transform to introduce new intensive variables. Note that
there are further transformed enthalpies H" and entropies S" that are not
discussed here. For larger reaction systems, further coenzyle concentrations can
be specified, but note that there is a maximum number of intensive variables that
can be specified for a given reaction system because one component must remain
unspecified.