Page 411 - Advances in Biomechanics and Tissue Regeneration
P. 411

21.3 BONE REMODELING AFTER THA                             409

           the base of the model, preventing its movement in x- and y-directions. The aforementioned natural and essential
           boundary conditions are represented schematically in Fig. 21.2A, while the magnitude and inclination of each load
           are presented in Table 21.2.
              Regarding material properties, the bone is considered isotropic with an initial uniform apparent density distribution
                           3
           equal to 2.1 g/cm and a Poisson’s coefficient of 0.3. The titanium implant has an elasticity modulus of 110 GPa and a
           Poisson’s coefficient of 0.32. This study does not consider interface elements between the implant and the bone tissue.
           The remodeling parameters α and β are assumed as 0.0 and 0.03, respectively.



           21.3.2 Prediction of Bone Remodeling

              Bone remodeling after implant placement is reproduced using the algorithm previously described. In Figs. 21.3
           and 21.4, the isomaps of the final trabecular architecture, von Mises effective stress, and principal stresses obtained
           with FEM and RPIM are respectively presented.
              Analyzing the trabecular architecture obtained, all numerical techniques present a trabecular morphology in agree-
           ment with Fig. 21.2B. However, only RPIM’s solution is able to predict the compressive trabeculae, even though less
           dense than expected. The tensile zones are more difficult to depict since the load is applied in the implant and not
           directly in the femoral bone. In Figs. 21.3C and 21.4C, the principal stress isomap σ 11 reveals the impact of the tensile
           load applied in the great trochanter.
              When comparing the normal trabecular morphology of a healthy femur, as obtained previously by Peyroteo et al.
           [8], with this model after THA, a significant difference is found. Because of stress shielding the obtained trabecular
           architecture is poorer when compared with a healthy case. Since the implant is stiffer than the bone, the applied loads
           and the consequent stress levels are backed up by the implant. As a result, the bone is not mechanically stimulated
           enough, and thus bone resorption occurs.





























           FIG. 21.2  (A) Natural and essential boundary conditions and (B) schematic representation of the major trabecular groups after THA.


                               TABLE 21.2 Load Cases Specifications

                               Load case    F 1 (N)    α 1 (°)   F 2 (N)   α 2 (°)   Load cycles
                               LC1          2317        24°      703        28°      6000
                               LC2          1158        15°      351        8°       2000
                               LC3          1548        56°      468        35°      2000






                                          II. MECHANOBIOLOGY AND TISSUE REGENERATION
   406   407   408   409   410   411   412   413   414   415   416