Page 145 - Biomedical Engineering and Design Handbook Volume 2, Applications
P. 145

124  MEDICAL DEVICE DESIGN

                                                                 Pump
                                           Chopper
                                                                              IR
                                    IR
                                                                            detector
                                    lamp
                                                           Sample

                                                          Reference



                                      LED                             Control
                                                  LED
                                                 detector             circuit
                                    FIGURE 4.9  Schematic showing the function of an infrared (IR) gas ana-
                                    lyzer. The chopper rotates, allowing light from the IR lamp to illuminate only
                                    one of the two gas-filled chambers (sample and reference) at a time. The IR
                                    light passes through the illuminated chamber, where it is differentially
                                    absorbed by the gases present. The IR detector measures the amount of IR
                                    light transmitted through the whole chamber. The LED and LED detector
                                    allow the control circuit to determine which of the two gas-filled chambers is
                                    illuminated at any time. The control circuit measures and linearizes the dif-
                                    ferential IR absorbance of the two chambers, and outputs the usable signal.


                       absorption in the reference chamber. This synchronization can be achieved by using a standard LED
                       and light detector to determine the position of the chopper opening. The IR analyzer is sensitive to the
                       pressure within the sample chamber, and thus requires either a constant flow through the chamber using
                       a stable pump, or no gas flow after a pump has filled the chamber with the gas to be analyzed. IR ana-
                       lyzers can be designed to have rapid response times. When used as a CO analyzer, CO is an interfer-
                                                                                    2
                       ing gas and must be removed or subtracted mathematically. H O is an interfering gas for almost all
                                                                   2
                       other gases and should be removed or equilibrated prior to analysis.
                         The zirconium fuel cell employs a zirconium substrate coated by platinum to create an electrode
                       sensitive only to oxygen. Oxygen diffuses through the platinum coating on one side, passes through the
                       zirconium, and completes the circuit on the other side of the fuel cell. So long as there is an oxygen
                       concentration difference on the two sides, the movement of oxygen ions creates a current and induces
                       a voltage, which is logarithmically related to the oxygen concentration difference. The zirconium is
                       heated to high temperature (> 700°C), requiring adequate warm-up time (20 to 30 minutes) and power
                       requirements not suited to highly portable applications. The analyzer is sensitive to the pressures within
                       it and thus requires a stable sample flow. It offers a rapid response time and is relatively insensitive to
                       interfering gases.
                         Paramagnetism refers to the propensity for certain molecules to align themselves when exposed
                       to a magnetic field. Oxygen exhibits very high magnetic susceptibility compared to other common
                       respiratory gases.  The paramagnetic oxygen analyzer introduces a gas mixture into a hollow
                       dumbbell-shaped structure suspended in a magnetic field. The greater the oxygen content, the greater
                       the force tending to move the dumbbell toward alignment in the field. The oxygen concentration may
                       be measured either as the deflection of the dumbbell or as the force required to prevent the dumb-
                       bell from moving. The analyzer is sensitive to pressure, and thus flow rates must be held steady dur-
                       ing measurement. Response times on modern analyzers are quite fast and may be suitable for rapid
                       sampling.
                         Emission spectroscopy is used to measure nitrogen concentrations. Nitrogen is drawn via a strong
                       vacuum through a needle valve into a Geisler tube, a very low pressure chamber where it is exposed
                       to a strong electric field (on the order of 25 kV) (Fig. 4.10). The N ionizes and emits light, which
                                                                        2
                       is filtered and picked up by a photodetector, where the signal is amplified and linearized, and output
   140   141   142   143   144   145   146   147   148   149   150