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Immune response         295


                 A. Simplified scheme of the immune response




                                                    Virus                         MHC protein
                                                                                  (class I)
                                      Antigen-presenting cells
                                                                                  MHC protein
                                  B lymphocyte            Macrophage              (class II)
                                                                        1
                            Antibody
                            (IgM)




                                                              2                     2
                                           Macrophage


                                                                          MHC protein
                                                                          (class I) with
                                      T cell receptor                     viral peptide
                                      for MHC-protein
                                      (class II)               T lymphocytes



                             MHC protein               3                                    3
                             (class II) with
                             virus fragment                   Resting     Resting
                                                              helper cells  cytotoxic
                                                                          T cells


                                     10
                                                IL- 1
                                    IL
                                                             Activated            5  IL- 1
                                                             helper cell
                                                                                                    IL- 2 6
                                                               IL- 2
                            11
                                                         4                   6               4
                                         9




                                       Plasma     Activated                  Activated
                                       cell       helper cells               cytotoxic
                                                                             T cells

                          12
                                                                                             Any body
                                                                                             cell







                                                                                  8            7
                              Antibody
                              (IgG)
                                                     Memory cells
                                                                                        IL = interleukin




           Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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