Page 306 - Color Atlas of Biochemistry

Immune response 297

A. Antigen receptors

Variable part
H chain
Constant part
L chain
• • • • • • • • • • Disulfide bond
• • • • • • • •

• • • •
Characteristic
• •
domain of the
superfamily Ig domain

α Chain β Chain • • α Chain α Chain β Chain
•
•
44 kDa 37 kDa 44 kDa 33 kDa 28 kDa
• •
•
• • α • α • • •
• • • • 2 • 1
•
•
β Micro-
2
• • • • globulin • •
•
•
• • • • • •
• •
α 12 kDa •• ••
3
•
•
C terminus
T cell receptor IgM MHC protein MHC protein CD8
(class I) (class II)

B. T cell activation
Viral peptide
Aufsicht
Cytotoxic T cell T cell activity

CD8
T cell
receptor

Virus
Presented 5 MHC
viral peptide protein
(class I)

Endoplasmic ATP ADP + P
4 Vesicular reticulum
transport
1
Proteo-
lysis
3 2
TAP Viral peptides
Virus-infected body cell

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.