Page 190 - Academic Press Encyclopedia of Physical Science and Technology 3rd BioChemistry
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Encyclopedia of Physical Science and Technology EN013D-617 July 27, 2001 11:42
230 Protein Synthesis
FIGURE 8 Steps in elongation. With the peptidyl–tRNA bound in the P-site and the incoming aminoacyl–tRNA in the
A-site, the peptidyl transferase activity of the large ribosomal subunit catalyzes peptide bond formation. The growing
polypeptide chain is then attached to the A-site-tRNA, and the deacylated tRNA is in the P-site. Elongation factor G
facilitates translocation of the peptidyl–tRNA to the P-site and the empty tRNA to the E-site prior to its release from
the ribosome.
