Page 208 - Fluid mechanics, heat transfer, and mass transfer
P. 208

MIXING
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                                                                     & Mixer discharge may be rapid, or it may take sub-
            6.2.7  Solids Mixing
                                                                       stantial time, particularly if the mixer is used as a
               . Give examples of solids mixing processes in pharma-
                                                                       surge vessel to feed a downstream process.
                ceutical, food, and chemical process industries.
                                                                     & Ideally, a mixer should not be used for storage
                 & In the pharmaceutical industry, small amounts of a
                                                                       capacity, because this can create a process bottle-
                  powdered active drug are carefully blended with
                                                                       neck, as the mixer cannot perform operations of
                  materials such as sugar, starch, cellulose, lactose, or
                                                                       storage and mixing concurrently.
                  lubricants.
                                                                     & Batch mixers are often used where
                 & In the food industry, many powdered consumer pro-
                                                                       ➢ Quality control requires strict batch control.
                  ducts result from custom mixed batches. Examples
                  include cake mix, ice tea, or Indian curry, a blend of  ➢ Ingredient properties change over time and com-
                  many fine spices.                                       pensation must be on a batch-by-batch basis.
                 & Thousands of processes in the chemical process      ➢ The mixer cannot be dedicated to a specific prod-
                  industries involve mixing or blending of specialty     uct line.
                  chemicals, explosives, fertilizers, dry powdered     ➢ Production quantities are small.
                  detergents, glass or ceramics, and rubber compounds.  ➢ Many formulations are produced on the same
               . What is the importance of uniformity in solids mixing   production line.
                on industrial scale?                                 & Major advantages of batch over continuous mixing
                 & The costs to business are increased substantially with  include the following:
                  poor mixing process implementation, when the re-     ➢ Lower installed and operating costs for small to
                  quirements are to address larger batch sizes, faster   medium capacities.
                  mixing times, energy conservation, and minimiza-     ➢ Lower cleaning costs when product changes are
                  tion of segregation.
                                                                         frequent.
                 & The goals of producing an acceptable mix, maintain-
                                                                       ➢ Production flexibility.
                  ing that mix through additional handling steps, and
                                                                       ➢ Premixing of minor ingredients is easily
                  verifying that both the mix and the finished product
                                                                         accomplished.
                  are sufficiently homogeneous are often difficult to
                                                                       ➢ Control of mixing time.
                  achieve on the first attempt.
                                                                     & In a continuous mixing process, the weighing, load-
                 & In many cases, the costs attributed to troubleshooting
                                                                       ing, mixing, and discharge steps occur continuously
                  a poorly performing mixing system can far outweigh
                                                                       and simultaneously. Product motion is generally
                  the initial investment costs. For example, an inade-
                                                                       directed from the feed point toward the outlet.
                  quate mix or segregation of a pharmaceutical drug
                  can cause the batch to fail, wasting millions of dollars  & Unlike batch mixers where product retention time is
                  involved, even though the equipment used to mix and  carefully controlled, with continuous mixers, mate-
                  transfer the powder can be a small percentage of this  rial retention time is not uniform and can be directly
                  cost.                                                affected by mixer speed, feed rate, mixer geometry,
               . Compare batch and continuous mixing processes for     and design of internals.
                solids mixing.                                       & Continuous mixing is typically used when
                 & A batch mixing process typically consists of three  ➢ A continuous, high production rate is required.
                  sequential steps, namely, weighing and loading the   ➢ Strict batch integrity is not essential.
                  components, mixing, and discharge of the mixed       ➢ Combining several process streams.
                  product.
                                                                       ➢ Smoothing out product variations.
                 & In a batch mixer, solids motion is confinedonly by the
                                                                     & Some of the advantages of a continuous mixing
                  vessel, and directional changes are frequent and
                                                                       system are the following:
                  critical with most units.
                                                                       ➢ Ease of equipment integration into continuous
                 & The retention time in a batch mixer is normally
                                                                         processes.
                  controlled, while for a continuous mixer, this is not
                                                                       ➢ Less opportunity for batch-to-batch variation
                  the case.
                                                                         caused by loading errors.
                 & Mixing cycles can last from a few seconds with high-
                                                                       ➢ Automation can improve quality and reduce labor
                  intensity units to 30 min or more where additional
                                                                         costs.
                  processing such as heating or cooling may be
                  involved.                                            ➢ Higher throughputs are often possible.
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