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Chapter 9 Applications of deep learning in biomedical engineering 253




               as a seed generative, and it has to be chosen randomly from
               Gaussian distribution. It helps to provide underlying structure
               of training data. It is used to synthesis the low-dimensional input
               domain to high-dimensional target domain [13].


               12.2 Discriminator network
                  It focuses on discrimination. It accesses the data from gener-
               ative network and attempts to discriminate between them. It is a
               normal classification model.
                  Critically, the generator can directly access the real images
               only by the interaction with the discriminator. The output of
               the discriminator only decides whether the two networks need
               to be optimized or not. The discriminator can access both the
               real images and the synthesis images [13].

               13. Applications of generative adversarial
                    network in biomedicine
                  GANs are a special type of neural network model where two
               networks are trained simultaneously, with one focused on image
               generation and the other centered on discrimination.
                  GAN is a neural network model, which comprised two net-
               works. These two networks process simultaneously in which
               one aims to generate image samples and other aims to classify
               them [14].
                  The applications of GAN are categorized into the following:
               • Image reconstruction
               • Image synthesis
               • Image segmentation
               • Image classification
               • Image detection
               • Image registration
                  The examples of GAN applications are as follows:
               • Semantic image editing, data augmentation, and style transfer
               • Image denoising and removing artifacts
               • Image synthesis such as generating synthetic samples for three
                  classes of liver lesions
               • Cross-modality synthesis such as brain CT image synthesis
                  from MR image [14]
               • Computing segmentation map
               • Chest abnormality classification, patch-based retinal vessel
                  classification, and cardiac disease diagnosis
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