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Ch34-I044963.fm  Page 165  Thursday, July 27, 2006  7:23 AM
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                  non-rotational tool. The former  is attached to a high  speed air turbine  spindle mounted  on C table. The
                  latter is directly  fixed  on C table through a jig. A workpiece  is mounted  on B table in both cases.
                  CREATION OF V-SHAPED MICROCHANNEL ARRAY CHIP

                  Figure 2 illustrates schematic views and dimensions of V-shaped microchannel  array chip. The chip has
                  a glass contact surface on its outside circumference, a shape like a bank in its center, hollows in both sides
                  of the bank and a through hole on the bottom of each hollow, which are an entrance and exit of blood. V-
                  shaped microchannel array, i.e., parallel-arranged  V-shaped microgrooves, is fabricated  on the bank. One
                  of the microgrooves is lOum in width, 5|j.m in depth and  lOOum in length. They are arranged  at intervals
                  of 10|im, and the total number of them is 250. The top surface  of the array has the same height as the glass
                  contact surface. The shapes to be machined are the microgrooves  and the glass contact  surface.

                  Fluidity  of blood, viz., compatibility  between blood and metal,  is evaluated as follows. A cover glass is
                  attached  to the top  surface  of the  chip,  and  blood  flow  comes  in  and  out  of the  holes  through  the
                  microchannel  array. The blood  flow through it is observed  over the cover glass. Consequently, the top
                  surface  of the chip, namely the glass contact  surface  and the top surface  of the array, must be a mirror
                  surface to prevent blood  from  leaking.

                  Figure  3 illustrates the employed  machining manner  of the V-shaped  microchannel  array  chip  in the
                  study. First, the top  surface  of the chip is machined with a large-diameter rotational tool  so as to be a
                  mirror surface. Secondly, the bank is formed  with a small-diameter rotational tool so that the width of its
                  top shape  can be  100)im. Tastly, the V-shaped  microchannel  array, i.e., the V-shaped  microgrooves, are
                  fabricated  with two  kinds of methods using a rotational  tool  or a non-rotational  tool. Each  tool  has a
                  diamond tip with the cutting edge of 90°. The former and the latter are respectively applied to the workpiece
                  made of gold and aluminum due to the results of the basic experiments that V-shaped microgrooving by

                                           Glass contact  surface
                  Glass contac.t  surface  ough  \  Bank  . .  (|>2mm         ,1-OWP,
                                    hole    .*_\—  \  16mm
                  Bank.                            \
                                               ol

                                                                                         5|im
                       (a) Oblique view           (b) Top view          (c) V-shaped microgrooves

                          Figure 2: Schematic views and dimensions of V-shaped microchannel  array chip

                                   Large-diameter
                                     rotational tool


                  (a) Mirror surface machining of the top surface of the chip
                            ---Small-diameter
                            \(\  rotational tool

                                                           i. With rotational tool  ii. With non-rotational tool
                                                        (c) Two kinds of V-shaped microgroove machining methods
                          (b) Forming of the bank
                                 Figure 3: Machining manner of V-shaped microchannel array
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