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Section 4.8  Design  Examples                                        259

                                         Magnitude of sensitivity vs. frequency
                           1.10             i
                                        1 '  '    !  .     II     .      i
                           1.05                        •N.   •        1    !
                                             I   " V j ^   ^-1  ^
                           1.00   . . ; _ .  ! '  -+-       i         i  J i  ' Mi
                          ivity   0.95   i                -                j
                          sensit   0.90   !   ! :  ; ! -
                                          i
                          de of   0.85   "T   t           u  -    r  -
                          gnitu   0.80   i.i  .1  ;  1    "  T'j         i j   ...: 1
                        2   0.75              .._.  1  .  -  1  -  •    "If  1
                                                                         i   .1
                           0.70
        FIGURE 4.22                               i  :  \             '.  •  :  i
       The magnitude of    0.65                            |i         :-4 ft
       the sensitivity of the           \    :    f   1                  i
       closed-loop system   0.60                  1    !     1
       for the Mars rover     1              10°            10             10-
       vehicle.                                Frequency  (rad/s)

                            As shown in Section 4.4, the  output  of the  closed-loop  system  with a unit  step
                        disturbance, T d{s) = 1/s, is
                                                                                            .
                                       y(O0) .  lim  J _ — I         1 1 . i               (4 68)
                                       / v  }        2                                     v  J
                                               s^o  \(s +  4s+  3 +K)j  s  3 + K
                        When  K  = 2, y(oo)  = 1/5. Because  we seek  to minimize the effect  of the  distur-
                        bance, it is clear that a larger  value of K would be desirable. An  increased  value  of
                        K, such as K  = 50, will further  reduce the effect  of the disturbance as well as reduce
                        the magnitude of the sensitivity (Equation 4.66). However, as we increase K beyond
                        K  = 50, the transient performance  of the system for the ramp input, r(t), begins to
                        deteriorate.  •

                        EXAMPLE 4.4    Blood pressure control during anesthesia

                        The objectives  of anethesia are to eliminate pain, awareness, and natural reflexes so
                        that  surgery can be conducted  safely.  Before  about  150 years  ago, alcohol, opium
                        and  cannabis  were  used  to achieve  these  goals, but they  proved  inadequate  [23].
                        Pain  relief  was insufficient  both in magnitude  and duration; too little pain  medica-
                        tion and  the patient felt great pain, too much medication  and the patient died or be-
                        came  comatose. In the  1850s ether  was  used  successfully  in the United  States in
                        tooth  extractions, and  shortly thereafter  other means  of achieving  unconsciousness
                        safely were developed, including the use of chloroform  and nitrous oxide.
                            In a modern  operating  room, the  depth  of anesthesia  is the responsibility of
                        the  anesthetist.  Many  vital  parameters,  such  as blood  pressure, heart  rate,  tem-
                        perature, blood  oxygenation, and exhaled  carbon  dioxide, are controlled  within
                        acceptable  bounds  by the anesthetist.  Of course, to ensure  patient  safety,  ade-
                        quate  anesthesia  must  be maintained  during the entire  surgical procedure. Any
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