Page 176 - Modern Derivatization Methods for Separation Sciences

Document Página 2 de 2

Alkyl halide reagents such as phenacyl bromide (PHB) [91-93], p-bromophenacyl bromide (BPB) [94-
99], α-bromo-2'-acetonaphtone (BAN) [100102] and panacyl bromide (PB) [103] react with carboxylic
acids in acetonitrile under mild conditions, and the reactions are catalyzed by a crown ether and
potassium ion, or organic bases such as triethylamine and ethylamine (Fig. 2.23a).

http://emedia.netlibrary.com/nlreader/nlreader.dll?bookid=17968&filename=Page_78.html 30/09/2003