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CHAPTER 11



                                            Electrochemical


                                   Surface Switches and



                                   Electronic Ion Pumps


                                   Based on Conjugated



                                                        Polymers





               Magnus Berggren* and Agneta Richter-Dahlfors †
               OBOE––Strategic Center for Organic Bioelectronics





          11.1  Electronic Control of Surface Properties
               In a vast number of biotechnological applications, the interface between
               an aqueous fluid and a solid surface is of great importance. This inter-
               face may serve as the anchoring site for biomolecules in biosensor sys-
               tems, act as a catalyst for chemical reactions, etc. In the technology area
               of microfluidics, major efforts have been devoted to design and engi-
               neer the chemistry and topography of solid surfaces in order to control
               the flow of liquids in dispensing and analysis systems of various com-
               plexity. In the cell biology field, surfaces have been shown to act as
               promoters for specific protein adsorption, and this effect has been uti-
               lized to dictate the specific proliferation and differentiation scheme of
               cultivated cells.  Numerous recent breakthroughs in material and sur-
                            1
               face science have provided a toolbox of technologies that today can be
               used to tailor-make the fluid-solid interface in order to express desired

               *Organic Electronics, ITN, Linköpings Universitet, Norrköping, Sweden.
               † Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
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