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                         A brief historical overview of microsensors development is presented here. The microsensors are made
                       possible by using integrated microfabrication technology, first developed for making integrated circuits.
                       Since the invention of the first transistor in 1947 and the successful demonstration of the integrated
                       circuits in 1971, technologies and equipment for building integrated and miniature circuit components
                       on semiconductor substrates (e.g., silicon and GaAs) have improved rapidly. The integration density
                       doubles every 12–18 months following the empirical Moore’s law. The integrated circuit technology
                       revolutionized the modern society by enabling low cost analog signal processors, digital logical units,
                       computer memories, and CCD cameras. These achievements should serve as evidence of the power of
                       integration and miniaturization technology.
                         Advanced signal processors such as analog ASIC (application specific integrated circuits) and CPU
                       (central processing units) are merely one aspect of a highly intelligent mechtronics system. Sensors are
                       of critical importance for mechantronics systems to interact with the physical world. In the 1970s, a few
                       researchers experimented with using IC fabrication technology to realize mechanical transduction ele-
                       ments on a silicon chip. H. Nathansan [1] developed floating gate transistors where the gate is made of
                       a suspended cantilever beam and its distance to the conducting channel can be adjusted using electrostatic
                       forces.  Work by several pioneering researchers resulted in the  first commercial pressure sensors [2],
                       accelerometers [3], integrated gas chromatometers, as well as the ink jet printer nozzle array [4,5].
                         There are several important advantages associated with integrated microsensors compared with con-
                       ventional macroscopic sensors. Miniaturization of sensors means that such sensors offer better spatial
                       resolution. In many cases, reduced inertia and thermal mass translate into higher mechanical resonant
                       frequency and lower thermal time constants. Since such sensors are fabricated using photolithography
                       methods, their costs can be low, as many identical units are made in parallel (if the demand is sufficiently
                       large). Further, since the geometric features of sensor components are defined by precision photolithog-
                       raphy, the uniformity and repeatability of the performance of such sensors are significantly improved
                       over conventional sensors. The capability to monolithically integrate sensors and integrated circuits
                       reduces the path length between sensors and circuits and increases the signal-to-noise ratio.

                       Fabrication Process of Integrated Microsensors
                       As mentioned previously, the microfabrication technology for microsensors was developed based on
                       integrated circuits-compatible platforms. As a result, silicon has historically been a predominant material
                       for microintegrated sensors. In other words, a majority of sensors are now made with silicon wafer as a
                       substrate. However, in recent years, new materials such as polymers are being applied to microfabrication.
                       Polymer materials offer lower costs than single crystal silicon wafers and, in some cases, simpler process-
                       ability, compared with semiconducting silicon. There are few examples of sensors that are entirely based
                       on polymer these days, because certain key sensing elements are not yet available in polymer format.
                       However, with the advancement of polymer microfabrication technology and organic semiconductors,
                       all-polymer sensors can be predicted for future use.
                         Microsensors and mechanical elements (notably cantilevers and diaphragms) can be made from silicon
                       substrates in a variety of ways. The two primary categories of fabrication methods are called bulk
                       micromachining and surface micromachining. In bulk machining, a portion of the silicon substrate is
                       removed using chemical wet etch or plasma-assisted dry etch to render freestanding mechanical members.
                       For silicon substrates, the following wet chemical etchants are frequently used: potassium hydroxide
                       (KOH), ethylene-diamine pyrocatecol (EDP), or tetramethyl ammonium hydroxide (TMAH). Dry etch-
                       ing methods use AC-excited plasma as an energetic source to selectively and anisotropically remove the
                       substrate materials. A review of etching solutions commonly used in the silicon microfabrication industry
                       and their respective etch rates on various materials can be found in [6].
                         In surface micromachining methods, a freestanding structure typically resides within a thin region
                       near the substrate surface. The fabrication process involves only layers on the surface of a substrate, hence
                       the name surface micromachining. The fabrication process is typically referred to as a sacrificial etching
                       method as well. First, a thin-film solid layer called the sacrificial layer is placed on the wafer surface. This
                       is followed by the deposition of a structural layer, which constitutes the mechanical structure (e.g.,


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