Page 304 - Thermodynamics of Biochemical Reactions

304 Mathematica Solutions to Problems

5.53164 5.54601 5.66019 5.98488 6.13662
5.53714 5.5948 5.86614 6.10926 6.15453
5.54145 5.62832 5.9385 6.12755 6.1566
0.107375 0.106755 0.101949 0.0894334 0.0841235
0.107137 0.104674 0.0938216 0.0850572 0.0835179
0.106951 0.103268 0.0911224 0.0844318 0.0834482
0.00065925 0.0062929 0.0416282 0.0509505 0.00908086
0.00284928 0.0234401 0.0631637 0.0188138 0.00218857
0.00453314 0.0334474 0.0578654 0.0124135 0.00136563

Reaction 9

rxthermotab[pg2+de==pep+h2o,~5,6,7,8,9~,~0,.1,.25~1
-0.828959 -0.989798 -2.0152 -3.7985 -4.37876
-0.891715 -1.47469 -3.25948 -4.28122 -4.44115
-0.939757 -1,76463 -3.59868 -4.34674 -4.44829
1.3971 1.49075 2.25448 4.62877 5.84954
1.43292 1.81281 3.7242 5.62385 5.99863
1.46096 2.03774 4.27029 5.77446 6.01593
-0.00760123 -0.0683949 -0.313273 -0.212886 -0.0319192
-0.0321025 -0.213665 -0.312677 -0.0680294 -0.00755601
-0.0501811 -0.274923 -0.257218 -0.0440393 -0.0047052
Reaction 10

rxthermotab[pep+adg+de==pyruvate+atp,{5,6,7,8,9},~0,.1,.25}1

-33.4613 -32.7661 -30.6224 -25.1722 -19.2526
-34.1841 -33.1449 -29.2617 -23.6955 -17.993
-34.4724 -33.1063 -28.8451 -23.2908 -17.5968
728017. 549974. 231625. 25700.8 2359.9
974465, 540772. 133784. 14166.3 1419.79
6
1.09465 10 630867. 113085. 12032.5 1210.04
0.150557 0.151752 0.700597 1.06297 1.01353
0.0719355 0.38045 0.915575 0.99698 0.999809
0.0826948 0.480624 0.927296 0.993667 0.999384

Net Reaction

rxthermotab[glucose+2*pi+2*adp+2*nadox+de==2*pyruvate+2*atp+2*nadred+2*h20,~5,6,7,8,9~,
{Or -1, -2511
-26.9029 -48.5056 -67.9556 -80.9971 -92.2429
-38.2553 -59.9344 -77.5099 -90.3854 -101.978
-42.0903 -63.6158 -80.8106 -93.5651 -105.141
8 11 14 16
51659.7 3.1461 10 8.0398 10 1.54878 10 1.44602 10
6 10 13 15 17
5.03504 10 3.16219 10 3.79375 10 6.83502 10 7.3388 10
7 11 14 16 18
2.36512 10 1.39618 10 1.43657 10 2.46488 10 2.62942 10
-3.70662 -3.76388 -2.84378 -1.97548 -1.98561
-3.90829 -3.56983 -2.55969 -2.07742 -2.00807
-3.92322 -3.50274 -2.5161 -2.07045 -2.00732
4.9 Calculate the standard transformed reaction Gibbs energies, apparent equilibrium constants, and changes in the binding
of hydrogen ions for the four reactions of gluconeogenesis that are different from those in glycolysis at 298.15 K, pHs 5, 6,