Page 420 - Advances in Biomechanics and Tissue Regeneration

418 Index

Mechanotransduction (Continued) oxygen consumption, 330 Neighborhood-based protocol (K-nn search
mesenchymal stem cells chondrogenesis simulated and measured profiles, 333–335, method), 12, 12f
(see Chondrogenesis, mesenchymal 334f Neo-Hookean strain-energy function, 99–100
stem cells) species concentrations Nernst equation, 120–121
nucleus deformation, 381 boundary conditions, 318 Nernst-Planck-Einstein equation, 121
routes of, 381f reaction-convection-diffusion Nerve tissues, 254–255
transcriptional regulators, 380 phenomena, 318 Nervous layer, eye, 4–5
skin mechanobiology, 350–351 source terms and diffusion, 321 Net traction force, 292–293, 295
smooth muscle cell, 108 3D finite element implementation Neumann boundary condition, 151
Medial collateral ligament (MCL), 182 spatial discretization, 322–326 neutral triangle, 247–248
Medial-lateral (M-L) locations, compression time integration, 326–327 Nitinol (NiTi) self-expanding colonic stents
force, 185 weak form, 321–322 biocompatibility, 33
Membrane capacitance, 118 Microstructural model, 68–69 characteristics, 35t
Membranous labyrinth, 22 Microvascular hyperplasia, 314 Choo stent, 40, 41f
M.E. M€ uller Straight Stem prosthesis of Migration tendency, stents, 37 customized parametric design
titanium alloy, 406 Mitosis phase, cell proliferation, 299 (see Customized self-expandable NiTi
Meniscus, 182–183 Modified Gianturco stents, 38, 39f colonic stents)
Mesenchymal stem cells (MSCs) Moment matrix, 177 esophacoil stent, 38, 39f
cartilage engineering, 370f Momentum conservation equation, 86 manufacturing process, 53
adipose tissue, 370–371 Mono-component silicone, 281 material parameters, 46t
bone marrow, 370 Monodomain model, 118–119 shaping process, 49
dental pulp, 371 Monte Carlo (MC) simulation, 9 strain-stress curves, 45–46f
peripheral blood, 371–372 ANOVA analysis, 10 Ultraflex stent, 38–40, 40f
synovium, 372 dataset generation, 10 NNRPIM. See Natural neighbor radial point
umbilical cord, 371 empirical distribution, 10 interpolation method (NNRPIM)
chondrogenesis (see Chondrogenesis, ex vivo inflation experiments, 9–10 Nodal connectivity, 406
mesenchymal stem cells) Kolmogorov-Smirnov hypothesis test, 10, Nodal-independent background integration
Meshless methods 11–12t mesh, 202
advantages, 202 mechanical corneal response, 10, 11f Noncontact tonometry, 4
vs. finite element method, 202 physiological stress state, 10 Nonlinear orthotropic hyperelastic strain
mechanical applications, 202 Morphing process, 161 energy function, 142
nodal-dependent constructions, 202 Moving least square (MLS) Nonlinear postbuckling analysis, 188, 188f
nodal discretization, 202 approximation, 140, 176–177 Nonrigid registration, 161
truly meshless methods, 202 Multisignaling extracellular matrix, cell Not-truly meshless method, 24
untrue meshless methods, 202 behavior
Mesh opening, stents, 37 cell-cell interactions, 308 O
Michaelis-Menten model, 330 cell net traction force vs. average cell O-Grid structures, 81–82
Microfiber model, 74–75 translocation, 301, 304f Ohm’s law, 117
Microfluidic devices, in vitro GBM models chemical gradient, 300 Olufsen model, 84
alive cells evolution, 332, 334f multicell migration, 300–301, 303f Organ-on-chip cell process. See Microfluidic
boundary conditions, 332 single cell morphology, 302–304, 305f devices, in vitro GBM models
cell death, 330 stiffness gradient, 300 Orientation-dependent feature (ODF), 204
cell leakage and oxygen supply, 335 thermal gradient, 300 Orthotropic material law, 165
cell population equations Murray’s law, 82 Osseointegration, 393
boundary conditions, 318 Musculoskeletal biomechanics Osteoarthritis
chemotaxis, 320 cartilage, 182 cell senescence, 368
differentiation, 319 knee joint (see Knee joint biomechanics) features, 367
diffusion, 320 Myocardium, 254 matrix-degrading proteases, 368
electrotaxis, 320 Myocardium conductance, 119 pericellular matrix, 368
mechanotaxis, 320 Myofibroblasts, 354–358 risk factors, 367–368
proliferation, 319 small injuries, 367–368
reaction-convection-diffusion N vascular endothelial growth factor, 368
phenomena, 318 Nail locking, 218 Osteoarthritis (OA), 181
thermotaxis, 320 Nanograting topography, 383–384 Osteocytes, 254
cell proliferation, 335, 335f Nasal septal cartilage, 369 Osteosynthesis, 228–229
extracellular matrix remodeling coupling, Natural neighbor radial point interpolation
321 method (NNRPIM) P
grow dichotomy, 329 mandibular bone remodeling, dental Pachymetry data, 5
initial conditions, 332 implants Palmaz-Schatz-type stent, 47, 47f
intercell culture parameter variability, 335 nodal distribution, 396, 396f Parametric proper orthogonal decomposition
model and parameters, 336 trabecular structure, 399–401f with interpolation (PODI) method, 146,
1D finite element implementation semicircular ducts, 3D-model, 29, 30f 147f, 150
spatial discretization, 329 trabecular bone RVE, 207–208, 209f Pentacam corneal topography, 5
time integration, 329 vestibular system, 24 Pericellular matrix (PCM), 364–365
unidimensional equations, 327–328 Navier-Stokes equations, 86 Perichondrium, 361–362
weak form, 328 N-cadherin, 380–381 Perilymph, 22