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Raman Detection of Car otenoids in Human T issue   213









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       4000                           1500

      Raman intensity  2000         Raman intensity  1000
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          0
                                          –600 –300  0  300  600
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                                            Distance from fovea (μm)
             Distance from fovea (μm)
                                      1000
        Raman intensity 400         Raman intensity  600
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           0                           200 0
            –600 –300  0  300  600      –900–600–300  0  300  600  900
              Distance from fovea (μm)      Distance from fovea (μm)
   FIGURE 7.12 (a) Pseudo-color-scaled, three-dimensional MP RRI images obtained from
   four healthy subjects, demonstrating signifi cant intersubject variations in MP levels,
   symmetries, and spatial extent. Note ring-like MP distribution with small central MP
   peak and overall low levels in one of the cases (lower left). All images are color coded
   with the same intensity bar. (b) Intensity plot profi les derived for each MP distribution
   from pixel intensity maps (22 × 1400 μm rectangles) running along nasal-temporal
   meridians through the center of the macula. (Reprinted with permission from Ref. 24.)
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